node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dnajb4 | hsp90aa1.1 | ENSDARP00000056895 | ENSDARP00000022302 | DnaJ heat shock protein family (Hsp40) member B4. | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | 0.649 |
dnajb4 | hsp90ab1 | ENSDARP00000056895 | ENSDARP00000014978 | DnaJ heat shock protein family (Hsp40) member B4. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.631 |
dnajb4 | hspa12a | ENSDARP00000056895 | ENSDARP00000106960 | DnaJ heat shock protein family (Hsp40) member B4. | Heat shock protein 12A. | 0.494 |
dnajb4 | hspa4a | ENSDARP00000056895 | ENSDARP00000026086 | DnaJ heat shock protein family (Hsp40) member B4. | Heat shock protein 4, like. | 0.882 |
dnajb4 | hspa4b | ENSDARP00000056895 | ENSDARP00000020214 | DnaJ heat shock protein family (Hsp40) member B4. | Heat shock protein 4b. | 0.821 |
dnajb4 | stip1 | ENSDARP00000056895 | ENSDARP00000100503 | DnaJ heat shock protein family (Hsp40) member B4. | Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein). | 0.660 |
dnajc7 | hsp90aa1.1 | ENSDARP00000131631 | ENSDARP00000022302 | DnaJ (Hsp40) homolog, subfamily C, member 7. | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | 0.723 |
dnajc7 | hsp90ab1 | ENSDARP00000131631 | ENSDARP00000014978 | DnaJ (Hsp40) homolog, subfamily C, member 7. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.712 |
dnajc7 | hspa12a | ENSDARP00000131631 | ENSDARP00000106960 | DnaJ (Hsp40) homolog, subfamily C, member 7. | Heat shock protein 12A. | 0.505 |
dnajc7 | hspa4a | ENSDARP00000131631 | ENSDARP00000026086 | DnaJ (Hsp40) homolog, subfamily C, member 7. | Heat shock protein 4, like. | 0.747 |
dnajc7 | hspa4b | ENSDARP00000131631 | ENSDARP00000020214 | DnaJ (Hsp40) homolog, subfamily C, member 7. | Heat shock protein 4b. | 0.830 |
dnajc7 | stip1 | ENSDARP00000131631 | ENSDARP00000100503 | DnaJ (Hsp40) homolog, subfamily C, member 7. | Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein). | 0.413 |
dnajc7 | stub1 | ENSDARP00000131631 | ENSDARP00000118937 | DnaJ (Hsp40) homolog, subfamily C, member 7. | STIP1 homology and U-Box-containing protein 1. | 0.509 |
gak | hspa12a | ENSDARP00000111020 | ENSDARP00000106960 | Cyclin G-associated kinase. | Heat shock protein 12A. | 0.643 |
gak | hspa4a | ENSDARP00000111020 | ENSDARP00000026086 | Cyclin G-associated kinase. | Heat shock protein 4, like. | 0.836 |
gak | hspa4b | ENSDARP00000111020 | ENSDARP00000020214 | Cyclin G-associated kinase. | Heat shock protein 4b. | 0.836 |
hsp90aa1.1 | dnajb4 | ENSDARP00000022302 | ENSDARP00000056895 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | DnaJ heat shock protein family (Hsp40) member B4. | 0.649 |
hsp90aa1.1 | dnajc7 | ENSDARP00000022302 | ENSDARP00000131631 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | DnaJ (Hsp40) homolog, subfamily C, member 7. | 0.723 |
hsp90aa1.1 | hsp90ab1 | ENSDARP00000022302 | ENSDARP00000014978 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.902 |
hsp90aa1.1 | hspa12a | ENSDARP00000022302 | ENSDARP00000106960 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | Heat shock protein 12A. | 0.762 |