STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnase1Deoxyribonuclease; Belongs to the DNase I family. (278 aa)    
Predicted Functional Partners:
galm
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
   
  
 0.621
pdia2
Protein disulfide-isomerase.
   
  
 0.597
ccdc25
Coiled-coil domain-containing protein 25; Belongs to the CCDC25 family.
      
 0.541
pla2g1b
Phospholipase A(2).
   
  
 0.523
onecut3a
One cut homeobox 3a.
    
 
 0.490
vps26b
Vacuolar protein sorting-associated protein 26B; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity).
      
 0.474
znf1153
Zinc finger protein 1153.
    
 
 0.465
ENSDARP00000137830
Si:dkey-179k24.2.
    
 
 0.465
tnfb
Tumor necrosis factor b (TNF superfamily, member 2).
    
 
 0.437
cpa1
Carboxypeptidase A1 (pancreatic).
   
  
 0.422
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.