STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nek2NIMA (Never in mitosis gene a)-related kinase 2. (440 aa)    
Predicted Functional Partners:
anapc4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.995
cdc20
Cell division cycle 20 homolog.
   
 0.993
cdc27
Cell division cycle 27.
   
 0.992
bub1ba
BUB1 mitotic checkpoint serine/threonine kinase Ba.
   
 0.984
bub1bb
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 
 0.967
anapc1
Anaphase-promoting complex subunit 1.
   
 0.967
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.966
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.952
fzr1a
Fizzy/cell division cycle 20 related 1 (Drosophila).
   
 
 0.950
cdc23
CDC23 (Cell division cycle 23, yeast, homolog).
   
 0.942
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.