Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fam53bProtein FAM53B; Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (ctnnb1) nuclear localization. Required for appendage regeneration by regulating cell proliferation. (379 aa)    
Predicted Functional Partners:
ccl34b.4
Chemokine (C-C motif) ligand 34b, duplicate 4.
      
 0.780
dcaf7
Ddb1 and cul4-associated factor 7.
    
 
 0.771
cyfip2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
      
 0.723
xkrx
XK-related protein.
      
 0.670
MSMP
Si:ch211-69e13.6.
      
 0.662
cnih2
Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs); Belongs to the cornichon family.
      
 0.638
cnih3
Cornichon family AMPA receptor auxiliary protein 3.
      
 0.638
glo1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
      
 0.617
ywhae2
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
    
 
 0.609
ywhae1
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1; Belongs to the 14-3-3 family.
    
 
 0.609
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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