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htra1b protein (Danio rerio) - STRING interaction network
"htra1b" - Serine protease HTRA1B in Danio rerio
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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htra1bSerine protease HTRA1B; Serine protease with a variety of targets, including extracellular matrix proteins and proteoglycans. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin- like growth factors (IGFs) by cleaving IGF-binding proteins. Inhibits signaling mediated by TGF-beta family members. Consequently, may regulate many physiological processes. Intracellularly, degrades TSC2, leading to the activation of TSC2 downstream targets ( [...] (476 aa)    
Predicted Functional Partners:
cilp2
Cartilage intermediate layer protein 2 (1255 aa)
           
  0.845
fgfbp2a
Fibroblast growth factor binding protein 2a (219 aa)
           
  0.789
TNXB
Tenascin XB (2285 aa)
           
  0.780
tysnd1
Trypsin domain containing 1 (565 aa)
           
  0.615
AHSG
alpha-2-HS-glycoprotein; Belongs to the fetuin family (386 aa)
           
  0.607
ahsg
alpha-2-HS-glycoprotein; Belongs to the fetuin family (455 aa)
           
  0.607
pigb
GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity) (536 aa)
     
   
  0.577
clpp
ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli) (266 aa)
   
 
  0.574
mrpl19
Mitochondrial ribosomal protein L19 (281 aa)
   
   
  0.565
zgc:158343
Zgc-158343 (208 aa)
           
  0.556
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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