STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hnrnpuaHeterogeneous nuclear ribonucleoprotein Ua. (760 aa)    
Predicted Functional Partners:
igf2bp1
Insulin-like growth factor 2 mRNA-binding protein 1; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in adult sensory neurons (By similarity). Regulates localized beta- actin/AC [...]
   
 0.621
syncrip
Synaptotagmin-binding, cytoplasmic RNA-interacting protein.
   
  0.618
syncripl
Synaptotagmin-binding, cytoplasmic RNA-interacting protein,-like.
   
  0.616
matr3l1.2
Matrin 3-like 1.1.
   
 
 0.594
pin4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4; May be involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to DNA (By similarity).
    
 
 0.578
hnrnpm
Heterogeneous nuclear ribonucleoprotein M.
   
 
 0.567
smg6
SMG6 nonsense mediated mRNA decay factor.
     
 0.566
smg5
SMG5 nonsense mediated mRNA decay factor.
   
 
 0.557
hnrnpub
Heterogeneous nuclear ribonucleoprotein Ub.
  
 
 
0.557
smg7
SMG7 nonsense mediated mRNA decay factor.
   
 0.552
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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