Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
rnf128aRing finger protein 128a. (389 aa)    
Predicted Functional Partners:
otub1a
Ubiquitin thioesterase.
    
 0.913
rom1a
Retinal outer segment membrane protein 1a.
    
 
 0.704
usp8
Ubiquitin-specific peptidase 8; Belongs to the peptidase C19 family.
    
 0.704
s100z
Protein S100; Belongs to the S-100 family.
      
 0.696
otub1b
Ubiquitin thioesterase.
    
 0.692
usp2b
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.689
rnf41
E3 ubiquitin-protein ligase NRDP1; Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins.
      
 0.681
prph2b
Peripherin 2b (retinal degeneration, slow).
    
 
 0.633
pnpla8
Patatin-like phospholipase domain-containing 8.
      
 0.630
tbk1
TANK-binding kinase 1.
    
 
 0.608
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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