Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
icnProtein S100; Belongs to the S-100 family. (95 aa)    
Predicted Functional Partners:
s100a10a
Protein S100; Belongs to the S-100 family.
   
 0.888
s100v2
S100 calcium-binding protein V2; Belongs to the S-100 family.
   
 
 0.858
s100a11
S100 calcium-binding protein A11.
   
 
 0.812
s100t
Protein S100; Belongs to the S-100 family.
     
  0.773
s100s
Protein S100; Belongs to the S-100 family.
     
  0.773
E7FAE7_DANRE
Si:ch211-105c13.3.
     
  0.773
anxa2a
Annexin.
   
 0.766
anxa1a
Annexin.
   
 0.766
s100u
S100 calcium-binding protein U; Belongs to the S-100 family.
   
 
 0.757
F1QQL4_DANRE
Si:ch211-125o16.4.
    
  0.745
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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