Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
gpx1aGlutathione peroxidase; Belongs to the glutathione peroxidase family. (191 aa)    
Predicted Functional Partners:
gsr
Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.999
sod2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.998
prdx6
Peroxiredoxin 6.
   
 0.958
gstp1
Pi-class glutathione S-transferase; Belongs to the GST superfamily.
   
 
 0.931
gss
Glutathione synthetase.
     
 0.921
gpx7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 
0.918
sod1
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.
   
 0.917
gpx8
Probable glutathione peroxidase 8; Belongs to the glutathione peroxidase family.
  
 
0.913
ppargc1a
Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.
     
 0.908
mgst2
Microsomal glutathione S-transferase 2.
     
 0.908
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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