STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. (284 aa)    
Predicted Functional Partners:
traf6
TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction.
   
 0.999
tlr2
Toll-like receptor 2.
   
 0.999
irak1
Interleukin-1 receptor-associated kinase 1.
   
 0.999
irak4
Interleukin-1 receptor-associated kinase 4.
   
 0.999
tlr4bb
Toll-like receptor 4b, duplicate b.
   
 0.998
tirap
Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein.
    
 0.998
tlr4ba
Toll-like receptor 4b, duplicate a.
   
 0.998
tlr4al
Toll-like receptor 4a, like.
   
 0.997
tlr9
Toll-like receptor 9; Belongs to the Toll-like receptor family.
    
 0.997
irf7
Interferon regulatory factor 7.
   
 0.990
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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