STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mthfd1bMethylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1b. (934 aa)    
Predicted Functional Partners:
gart
Phosphoribosylglycinamide formyltransferase.
 
 0.997
shmt1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.991
mthfr
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.991
ftcd
Formimidoyltransferase cyclodeaminase.
  
 
 0.990
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
  
 0.986
shmt2
Serine hydroxymethyltransferase 2 (mitochondrial).
  
 0.984
tyms
Thymidylate synthetase.
  
 
 0.980
mthfd2l
Methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 2-like.
  
 
0.979
mthfd2
Mthfd2 protein.
  
 
0.979
dhfr
Dihydrofolate reductase.
  
 
 0.977
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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