Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tbc1d17TBC1 domain family, member 17. (639 aa)    
Predicted Functional Partners:
fis1
Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
    
 0.972
tbc1d15
TBC1 domain family, member 15.
  
 
0.951
F1QYV4_DANRE
Si:dkey-13a21.4.
     
 0.945
rab7a
RAB7a, member RAS oncogene family.
   
 0.861
rab7b
RAB7b, member RAS oncogene family.
    
 0.837
zgc:100918
Zgc:100918.
    
 0.837
rab8a
RAB8A, member RAS oncogene family.
    
 0.739
PCMTD2
Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2.
      
 0.714
ubxn8
UBX domain protein 8.
   
 
 0.713
pcmtd2a
Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain-containing 2a.
      
 0.681
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.