STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zbtb8osProtein archease; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with ddx1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation (By similarity); Belongs to the archease family. (162 aa)    
Predicted Functional Partners:
rtcb
RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
  
 0.976
rtraf
RNA transcription, translation and transport factor protein; RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Component of the tRNA-splicing ligase complex.
   
 
 0.780
C9H2orf49
Ashwin; Belongs to the ashwin family.
   
 
 0.760
etf1b
Eukaryotic translation termination factor 1b.
  
    0.681
etf1a
Eukaryotic translation termination factor 1a.
  
    0.681
fam98b
Family with sequence similarity 98 member B.
    
 0.678
ddx1
DEAD (Asp-Glu-Ala-Asp) box helicase 1.
      
 0.567
im:7138535
Im:7138535.
     
  0.540
fam98a
Family with sequence similarity 98 member A.
     
  0.540
thumpd2
THUMP domain-containing 2.
      
 0.502
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.