Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adra1baAdrenoceptor alpha 1Ba. (486 aa)    
Predicted Functional Partners:
gnaq
Guanine nucleotide-binding protein (G protein), q polypeptide.
    
 0.936
gna14
Guanine nucleotide-binding protein (G protein), alpha 14.
    
  0.918
gna14a
Guanine nucleotide-binding protein (G protein), alpha 14a.
    
 0.907
gna12a
Guanine nucleotide-binding protein (G protein) alpha 12a.
    
 0.894
ENSDARP00000147214
Uncharacterized protein.
    
 0.894
gna13b
Guanine nucleotide-binding protein (G protein), alpha 13b.
    
 0.893
gna13a
Guanine nucleotide-binding protein (G protein), alpha 13a.
    
 0.893
gna11b
Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).
    
 0.891
gna11a
Guanine nucleotide-binding protein (G protein), alpha 11a (Gq class).
    
 0.891
gngt1
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.890
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.