STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trhPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems; Belongs to the TRH family. (199 aa)    
Predicted Functional Partners:
trhrb
Thyrotropin-releasing hormone receptor b; Belongs to the G-protein coupled receptor 1 family.
     
 0.994
trhr2
Novel protein similar to vertebrate thyrotropin-releasing hormone receptor (TRHR); Belongs to the G-protein coupled receptor 1 family.
     
 0.983
trhra
Thyrotropin-releasing hormone receptor a; Belongs to the G-protein coupled receptor 1 family.
     
 0.954
ENSDARP00000138362
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
     
 0.944
oxt
Oxytocin; Belongs to the vasopressin/oxytocin family.
   
 
 0.919
crhb
Corticotropin-releasing hormone b.
   
  
 0.906
crha
Corticotropin-releasing hormone a.
      
 0.896
npy
C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family.
   
  
 0.881
ghrh
Growth hormone-releasing hormone.
   
  
 0.852
pomca
Pro-opiomelanocortin protein.
      
 0.851
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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