Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trhPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems; Belongs to the TRH family. (199 aa)    
Predicted Functional Partners:
trhra
Thyrotropin-releasing hormone receptor a; Belongs to the G-protein coupled receptor 1 family.
    
 0.998
trhrb
Thyrotropin-releasing hormone receptor b; Belongs to the G-protein coupled receptor 1 family.
    
 0.996
trhr2
Novel protein similar to vertebrate thyrotropin-releasing hormone receptor (TRHR); Belongs to the G-protein coupled receptor 1 family.
    
 0.994
ENSDARP00000138362
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
 0.989
crhb
Corticotropin-releasing hormone b.
   
  
 0.907
crha
Corticotropin-releasing hormone a.
      
 0.900
pomca
Pro-opiomelanocortin protein.
      
 0.892
prl
Prolactin.
      
 0.876
oxt
Oxytocin; Belongs to the vasopressin/oxytocin family.
   
  
 0.840
prl2
Prolactin 2.
      
 0.839
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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