Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ppp1r14aaProtein phosphatase 1, regulatory (inhibitor) subunit 14Aa. (152 aa)    
Predicted Functional Partners:
ppp1r12a
Protein phosphatase 1 regulatory subunit 12A; Regulates myosin phosphatase activity.
    
 0.990
ppp1cbl
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.968
ppp1r12c
Protein phosphatase 1, regulatory subunit 12C.
    
 0.952
ppp1r14ab
Protein phosphatase 1, regulatory (inhibitor) subunit 14Ab.
     
  0.944
ENSDARP00000154801
PRKG1_interact domain-containing protein.
    
  0.944
ppp1caa
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.936
ppp1cb
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.931
ppp1cab
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.917
ppp1cc
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.873
Zmp:0000001167
ANK_REP_REGION domain-containing protein.
    
  0.871
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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