Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ccnl1bCyclin-L1; Involved in pre-mRNA splicing. (498 aa)    
Predicted Functional Partners:
cdk11b
Cyclin-dependent kinase 11B.
   
 
 0.876
golim4b
Golgi integral membrane protein 4b.
      
 0.799
selenot1b
Thioredoxin reductase-like selenoprotein T1b; Selenoprotein with thioredoxin reductase-like oxidoreductase activity.
      
 0.760
cdk10
Cyclin-dependent kinase 10; Belongs to the protein kinase superfamily.
   
 
 0.701
ptx3b
Pentraxin 3, long b.
      
 0.661
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity).
     
 0.656
sap30bp
SAP30-binding protein.
    
   0.638
cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.
      
 0.636
GPATCH2
Si:ch73-21k16.4.
   
 
 0.607
nav2a
Neuron navigator 2a.
    
 
 0.607
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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