Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sgk2bSerum/glucocorticoid-regulated kinase 2b; Belongs to the protein kinase superfamily. (404 aa)    
Predicted Functional Partners:
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.962
A3KQ53_DANRE
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
     
  0.934
sgk1
Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
     
  0.934
pdpk1b
3-phosphoinositide-dependent protein kinase 1b.
    
 0.918
pdpk1a
3-phosphoinositide-dependent protein kinase 1a.
    
 0.918
foxo1a
Forkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye.
    
 0.900
foxo3a
Forkhead box O3A.
    
 0.884
foxo3b
Forkhead box O3b.
    
 0.884
foxo4
Forkhead box O4.
    
 0.884
foxo6a
Forkhead box O6 a.
    
 0.884
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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