STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aqp4Si:ch211-192k9.1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (320 aa)    
Predicted Functional Partners:
aqp12
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
   
 
 0.906
trpv4
Transient receptor potential cation channel, subfamily V, member 4.
    
 
 0.902
aqp11
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
     
 0.893
cav1
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
   
 
 0.766
aqp7
Aquaporin 7; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.736
aqp3a
Aqp3 protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.729
aqp9b
Aquaporin 9b; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.724
aqp8a.1
Aquaporin 8a, tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.711
gfap
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  
 0.690
lrrc8aa
Leucine-rich repeat-containing 8 VRAC subunit Aa.
   
  
 0.690
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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