STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ormdl1ORM1-like protein 1; Negative regulator of sphingolipid synthesis; Belongs to the ORM family. (153 aa)    
Predicted Functional Partners:
sptssa
Serine palmitoyltransferase small subunit A; Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference (By similarity). Belongs to the SPTSS family. SPTSSA subfamily.
    
 0.988
sptssb
Serine palmitoyltransferase small subunit B; Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference (By similarity). Belongs to the SPTSS family. SPTSSB subfamily.
     
 0.961
sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
    
 
 0.893
sptlc2b
Serine palmitoyltransferase, long chain base subunit 2b.
    
 0.802
sptlc2a
Serine palmitoyltransferase, long chain base subunit 2a.
    
 0.802
sptlc3
Serine palmitoyltransferase, long chain base subunit 3.
    
 0.802
cers5
Ceramide synthase 5.
    
 
 0.614
ism1
Isthmin-1; May specifically influence certain angiogenesis process.
    
 
 0.588
ism2b
Isthmin-2.
    
 
 0.588
cers3b
Ceramide synthase 3b.
    
 
 0.565
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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