chrna1 protein (Danio rerio) - STRING interaction network

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chrna1

Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (456 aa)

Predicted Functional Partners:

chrnd

0.957

lypd6

0.952

chrne

0.950

chrnb1

0.945

chrng

0.944

chrnb1l

0.942

chrna6

0.939

chrnb2

0.939

chrnb4

0.939

chrnb5b

0.939

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
chrna1	chrna6	ENSDARP00000021860	ENSDARP00000038141	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	Cholinergic receptor, nicotinic, alpha 6.	0.939
chrna1	chrnb1	ENSDARP00000021860	ENSDARP00000092302	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	Cholinergic receptor, nicotinic, beta 1 (muscle).	0.945
chrna1	chrnb1l	ENSDARP00000021860	ENSDARP00000034131	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	Cholinergic receptor, nicotinic, beta 1 (muscle)-like.	0.942
chrna1	chrnb2	ENSDARP00000021860	ENSDARP00000041624	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	Cholinergic receptor, nicotinic, beta 2.	0.939
chrna1	chrnb4	ENSDARP00000021860	ENSDARP00000138900	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	Cholinergic receptor, nicotinic, beta 4 (neuronal).	0.939
chrna1	chrnb5b	ENSDARP00000021860	ENSDARP00000142507	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	Cholinergic receptor, nicotinic, beta 5b.	0.939
chrna1	chrnd	ENSDARP00000021860	ENSDARP00000016537	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	Cholinergic receptor, nicotinic, delta (muscle).	0.957
chrna1	chrne	ENSDARP00000021860	ENSDARP00000116514	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	Cholinergic receptor, nicotinic, epsilon.	0.950
chrna1	chrng	ENSDARP00000021860	ENSDARP00000110378	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	Cholinergic receptor, nicotinic, gamma.	0.944
chrna1	lypd6	ENSDARP00000021860	ENSDARP00000013064	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	Ly6/PLAUR domain-containing protein 6; Acts as an important regulator of embryogenesis through its enhancement of Wnt/beta-catenin signaling. Positively regulates Wnt/beta-catenin signaling by ensuring phosphorylation of lrp6 specifically in plasma membrane rafts and its subsequent internalization into signaling-competent vesicles. Essential for the wnt8-mediated patterning of the mesoderm and neuroectoderm during gastrulation.	0.952
chrna6	chrna1	ENSDARP00000038141	ENSDARP00000021860	Cholinergic receptor, nicotinic, alpha 6.	Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.	0.939
chrna6	chrnb1	ENSDARP00000038141	ENSDARP00000092302	Cholinergic receptor, nicotinic, alpha 6.	Cholinergic receptor, nicotinic, beta 1 (muscle).	0.904
chrna6	chrnb1l	ENSDARP00000038141	ENSDARP00000034131	Cholinergic receptor, nicotinic, alpha 6.	Cholinergic receptor, nicotinic, beta 1 (muscle)-like.	0.903
chrna6	chrnb2	ENSDARP00000038141	ENSDARP00000041624	Cholinergic receptor, nicotinic, alpha 6.	Cholinergic receptor, nicotinic, beta 2.	0.908
chrna6	chrnb4	ENSDARP00000038141	ENSDARP00000138900	Cholinergic receptor, nicotinic, alpha 6.	Cholinergic receptor, nicotinic, beta 4 (neuronal).	0.909
chrna6	chrnb5b	ENSDARP00000038141	ENSDARP00000142507	Cholinergic receptor, nicotinic, alpha 6.	Cholinergic receptor, nicotinic, beta 5b.	0.904
chrna6	chrnd	ENSDARP00000038141	ENSDARP00000016537	Cholinergic receptor, nicotinic, alpha 6.	Cholinergic receptor, nicotinic, delta (muscle).	0.900
chrna6	chrne	ENSDARP00000038141	ENSDARP00000116514	Cholinergic receptor, nicotinic, alpha 6.	Cholinergic receptor, nicotinic, epsilon.	0.904
chrna6	chrng	ENSDARP00000038141	ENSDARP00000110378	Cholinergic receptor, nicotinic, alpha 6.	Cholinergic receptor, nicotinic, gamma.	0.906
chrna6	lypd6	ENSDARP00000038141	ENSDARP00000013064	Cholinergic receptor, nicotinic, alpha 6.	Ly6/PLAUR domain-containing protein 6; Acts as an important regulator of embryogenesis through its enhancement of Wnt/beta-catenin signaling. Positively regulates Wnt/beta-catenin signaling by ensuring phosphorylation of lrp6 specifically in plasma membrane rafts and its subsequent internalization into signaling-competent vesicles. Essential for the wnt8-mediated patterning of the mesoderm and neuroectoderm during gastrulation.	0.945

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