STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chrna1Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (456 aa)    
Predicted Functional Partners:
chrnb1
Cholinergic receptor, nicotinic, beta 1 (muscle).
  
0.919
chrne
Cholinergic receptor, nicotinic, epsilon.
  
0.897
chrnd
Cholinergic receptor, nicotinic, delta (muscle).
   
0.885
chrng
Cholinergic receptor, nicotinic, gamma.
   
0.874
chrnb1l
Cholinergic receptor, nicotinic, beta 1 (muscle)-like.
  
0.869
chrna4b
Neuronal nicotinic acetylcholine receptor alpha 4 subunit.
  
0.867
chrna2a
Cholinergic receptor, nicotinic, alpha 2a (neuronal).
  
0.862
chrnb4
Cholinergic receptor, nicotinic, beta 4 (neuronal).
  
0.860
rapsn
Receptor-associated protein of the synapse, 43kD.
   
 
 0.833
dok7
Docking protein 7.
   
  
 0.813
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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