Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kcnj1bPotassium inwardly rectifying channel subfamily J member 1b. (375 aa)    
Predicted Functional Partners:
ano10b
Anoctamin.
      
 0.800
kcnk5b
Potassium channel, subfamily K, member 5b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
 0.742
kcnk9
Potassium channel, subfamily K, member 9; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.734
slc24a4a
Solute carrier family 24 member 4a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.670
ano10a
Anoctamin-10; Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1 (By similarity).
      
 0.594
slc12a7a
Solute carrier family 12 member 7a.
      
 0.552
thtpa
Thiamine triphosphatase.
      
 0.552
A3KQ53_DANRE
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
     
 0.527
sgk1
Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
     
 0.527
kcnj16
Potassium inwardly rectifying channel subfamily J member 16.
  
 
0.523
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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