node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abcb11a | mid1ip1b | ENSDARP00000047400 | ENSDARP00000021980 | ATP-binding cassette, sub-family B (MDR/TAP), member 11a. | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.480 |
abcb11a | nxph2a | ENSDARP00000047400 | ENSDARP00000116713 | ATP-binding cassette, sub-family B (MDR/TAP), member 11a. | Neurexophilin; May be signaling molecules that resemble neuropeptides. | 0.586 |
abcb11a | nxph2b | ENSDARP00000047400 | ENSDARP00000133274 | ATP-binding cassette, sub-family B (MDR/TAP), member 11a. | Neurexophilin; May be signaling molecules that resemble neuropeptides. | 0.628 |
abhd2b | cd74a | ENSDARP00000067326 | ENSDARP00000002547 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | CD74 molecule, major histocompatibility complex, class II invariant chain a. | 0.479 |
abhd2b | lyrm5b | ENSDARP00000067326 | ENSDARP00000113978 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | 0.744 |
abhd2b | mid1ip1b | ENSDARP00000067326 | ENSDARP00000021980 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.743 |
abhd2b | mthfd1l | ENSDARP00000067326 | ENSDARP00000061913 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1-like. | 0.540 |
abhd2b | nt5c2l1 | ENSDARP00000067326 | ENSDARP00000020283 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 5'-nucleotidase, cytosolic II,-like 1. | 0.479 |
cd74a | abhd2b | ENSDARP00000002547 | ENSDARP00000067326 | CD74 molecule, major histocompatibility complex, class II invariant chain a. | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 0.479 |
cd74a | lyrm5b | ENSDARP00000002547 | ENSDARP00000113978 | CD74 molecule, major histocompatibility complex, class II invariant chain a. | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | 0.481 |
cd74a | mid1ip1b | ENSDARP00000002547 | ENSDARP00000021980 | CD74 molecule, major histocompatibility complex, class II invariant chain a. | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.533 |
lyrm5b | abhd2b | ENSDARP00000113978 | ENSDARP00000067326 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 0.744 |
lyrm5b | cd74a | ENSDARP00000113978 | ENSDARP00000002547 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | CD74 molecule, major histocompatibility complex, class II invariant chain a. | 0.481 |
lyrm5b | mid1ip1b | ENSDARP00000113978 | ENSDARP00000021980 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.743 |
lyrm5b | mthfd1l | ENSDARP00000113978 | ENSDARP00000061913 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | Methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1-like. | 0.548 |
lyrm5b | nt5c2l1 | ENSDARP00000113978 | ENSDARP00000020283 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | 5'-nucleotidase, cytosolic II,-like 1. | 0.480 |
mid1ip1a | mid1ip1b | ENSDARP00000060149 | ENSDARP00000021980 | Mid1-interacting protein 1A; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.707 |
mid1ip1b | abcb11a | ENSDARP00000021980 | ENSDARP00000047400 | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | ATP-binding cassette, sub-family B (MDR/TAP), member 11a. | 0.480 |
mid1ip1b | abhd2b | ENSDARP00000021980 | ENSDARP00000067326 | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 0.743 |
mid1ip1b | cd74a | ENSDARP00000021980 | ENSDARP00000002547 | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | CD74 molecule, major histocompatibility complex, class II invariant chain a. | 0.533 |