Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bckdkProtein-serine/threonine kinase. (428 aa)    
Predicted Functional Partners:
bckdha
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.942
psmc2
Proteasome (Prosome, macropain) 26S subunit, ATPase 2; Belongs to the AAA ATPase family.
 
    
 0.899
psmc6
Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family.
 
 
    0.840
psmc5
Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family.
 
 
  
 0.833
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
   
 0.814
psmc3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
 
 
  
 0.788
trim35-9
Tripartite motif-containing 35-9.
    
 
 0.781
chchd3b
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
      
 0.780
psmc1b
Proteasome (Prosome, macropain) 26S subunit, ATPase, 1b; Belongs to the AAA ATPase family.
 
 
  
 0.761
dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.761
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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