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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
itkTyrosine-protein kinase. (616 aa)    
Predicted Functional Partners:
lcp2a
Lymphocyte cytosolic protein 2a.
   
 0.788
grb2b
Growth factor receptor-bound protein 2b.
   
 0.712
blnk
B cell linker.
   
 
 0.707
cd247
CD247 molecule.
   
 
 0.678
grap2a
GRB2-related adaptor protein 2a.
   
 0.658
plcg1
Phosphoinositide phospholipase C.
   
0.636
syk
Tyrosine-protein kinase.
  
0.634
vav3b
Vav 3 guanine nucleotide exchange factor b.
   
 0.614
vav2
Vav 2 guanine nucleotide exchange factor.
   
 0.614
havcr2
Hepatitis A virus cellular receptor 2.
    
 
 0.601
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.