angptl6 protein (Danio rerio) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E7EZT8_DANRE	angptl6	ENSDARP00000093294	ENSDARP00000022066	Si:ch211-262i1.5.	Angiopoietin-like 6.	0.424
LOC566646	angptl6	ENSDARP00000134449	ENSDARP00000022066	Si:ch211-9d9.1.	Angiopoietin-like 6.	0.424
TMCC1	angptl6	ENSDARP00000067638	ENSDARP00000022066	Transmembrane and coiled-coil domain family 1.	Angiopoietin-like 6.	0.594
angptl6	E7EZT8_DANRE	ENSDARP00000022066	ENSDARP00000093294	Angiopoietin-like 6.	Si:ch211-262i1.5.	0.424
angptl6	LOC566646	ENSDARP00000022066	ENSDARP00000134449	Angiopoietin-like 6.	Si:ch211-9d9.1.	0.424
angptl6	TMCC1	ENSDARP00000022066	ENSDARP00000067638	Angiopoietin-like 6.	Transmembrane and coiled-coil domain family 1.	0.594
angptl6	colec11	ENSDARP00000022066	ENSDARP00000016314	Angiopoietin-like 6.	Collectin-11; Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis [...]	0.475
angptl6	dmap1	ENSDARP00000022066	ENSDARP00000061678	Angiopoietin-like 6.	DNA methyltransferase 1-associated protein 1.	0.414
angptl6	eif3g	ENSDARP00000022066	ENSDARP00000027672	Angiopoietin-like 6.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.	0.414
angptl6	podn	ENSDARP00000022066	ENSDARP00000119380	Angiopoietin-like 6.	Podocan.	0.412
angptl6	raver1	ENSDARP00000022066	ENSDARP00000109981	Angiopoietin-like 6.	Ribonucleoprotein, PTB-binding 1.	0.446
angptl6	tek	ENSDARP00000022066	ENSDARP00000055680	Angiopoietin-like 6.	Tyrosine-protein kinase receptor Tie-2; Tyrosine-protein kinase that acts as cell-surface receptor for angiopoietins and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Can activate or inhibit angiogenesis, depending on the context. Angiopoietin signaling triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors (By similarity).	0.435
angptl6	tie1	ENSDARP00000022066	ENSDARP00000147239	Angiopoietin-like 6.	Tyrosine-protein kinase receptor Tie-1; Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.	0.540
colec11	angptl6	ENSDARP00000016314	ENSDARP00000022066	Collectin-11; Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis [...]	Angiopoietin-like 6.	0.475
colec11	podn	ENSDARP00000016314	ENSDARP00000119380	Collectin-11; Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis [...]	Podocan.	0.409
dmap1	angptl6	ENSDARP00000061678	ENSDARP00000022066	DNA methyltransferase 1-associated protein 1.	Angiopoietin-like 6.	0.414
dmap1	eif3g	ENSDARP00000061678	ENSDARP00000027672	DNA methyltransferase 1-associated protein 1.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.	0.434
dmap1	raver1	ENSDARP00000061678	ENSDARP00000109981	DNA methyltransferase 1-associated protein 1.	Ribonucleoprotein, PTB-binding 1.	0.527
eif3g	angptl6	ENSDARP00000027672	ENSDARP00000022066	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.	Angiopoietin-like 6.	0.414
eif3g	dmap1	ENSDARP00000027672	ENSDARP00000061678	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.	DNA methyltransferase 1-associated protein 1.	0.434

page 1 of 2

Server load: low (14%) [HD]

Share

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About