Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
slc25a6Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)    
Predicted Functional Partners:
vdac3
Voltage-dependent anion channel 3.
   
 0.918
vdac1
Voltage-dependent anion channel 1.
   
 0.911
vdac2
Voltage-dependent anion channel 2.
   
 0.898
zgc:56235
Zgc:56235.
   
 0.898
cycsb
Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
   
 0.866
uqcrfs1
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
 
 0.854
ppid
Peptidylprolyl isomerase D (Cyclophilin D).
    
 0.853
atp5fa1
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.833
tspo
Translocator protein.
   
 0.817
atp5pb
ATP synthase peripheral stalk-membrane subunit b.
   
 
 0.813
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]