Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
chgaChromogranin A. (369 aa)    
Predicted Functional Partners:
ccz1
Vacuolar fusion protein CCZ1 homolog.
    
 
 0.806
syt14b
Synaptotagmin XIVb.
      
 0.737
scn4ba
Voltage-gated sodium channel beta 4 subunit locus 1.
      
 0.683
foxb1b
Forkhead box B1b.
      
 0.665
pcsk1nl
Proprotein convertase subtilisin/kexin type 1 inhibitor,-like.
   
  
 0.626
rab39bb
RAB39B, member RAS oncogene family b.
   
  
 0.603
pnoca
Prepronociceptin a.
      
 0.594
mon1bb
MON1 secretory-trafficking family member Bb.
    
 
 0.583
mon1a
MON1 secretory-trafficking family member A.
    
 
 0.583
gripap1
GRIP1-associated protein 1.
    
 
 0.583
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (28%) [HD]