STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnd1bRho family GTPase 1 like. (232 aa)    
Predicted Functional Partners:
itsn2a
Intersectin 2a.
    
 
 0.791
itsn2b
Intersectin 2b.
   
 
 0.791
itsn1
Intersectin 1 (SH3 domain protein).
   
 
 0.762
flj11011l
Probable ubiquitin-conjugating enzyme E2 W-B; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in degradation of misfolded chaperone substrate and DNA repair.
   
 
 0.742
fam217b
Family with sequence similarity 217 member B.
      
 0.741
manea
Mannosidase, endo-alpha.
   
 
 0.734
tagapb
T cell activation RhoGTPase-activating protein b.
   
 
 0.718
arhgap5
Rho GTPase-activating protein 5.
   
 0.713
rapgef1a
Rap guanine nucleotide exchange factor (GEF) 1a.
    
 
 0.713
rock2a
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
 0.707
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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