Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rnd1bRho family GTPase 1 like. (232 aa)    
Predicted Functional Partners:
arhgef12a
Rho guanine nucleotide exchange factor (GEF) 12a.
   
 0.774
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11.
   
 0.774
rock2a
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.753
arhgap5
Rho GTPase-activating protein 5.
   
 0.745
gna13b
Guanine nucleotide-binding protein (G protein), alpha 13b.
   
 0.739
arhgap35a
Rho GTPase-activating protein 35a.
    
 0.736
rapgef1a
Rap guanine nucleotide exchange factor (GEF) 1a.
    
 0.726
arhgef3
Rho guanine nucleotide exchange factor (GEF) 3.
    
 0.724
plxnb1b
Plexin b1b.
    
  0.723
fam217b
Family with sequence similarity 217 member B.
      
 0.719
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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