Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tfdp1bTranscription factor. (385 aa)    
Predicted Functional Partners:
rbl2
Retinoblastoma-like 2 (p130).
   
 0.886
tmco3
Transmembrane and coiled-coil domains 3.
 
    
 0.864
e2f3
E2F transcription factor 3.
   
 0.793
e2f4
E2F transcription factor 4.
   
 0.783
e2f5
E2F transcription factor 5.
  
 0.753
rb1
Retinoblastoma 1.
   
 0.746
rbl1
Retinoblastoma-like 1 (p107).
   
 0.746
e2f1
E2F transcription factor 1.
   
 0.736
Q29RF1_DANRE
Si:ch211-195d17.2 protein.
  
 0.707
E7FFJ8_DANRE
Si:ch211-160f23.5.
   
 0.645
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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