Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptrhd1Peptidyl-tRNA hydrolase domain-containing 1. (126 aa)    
Predicted Functional Partners:
pof1b
POF1B actin-binding protein.
      
 0.783
cyp39a1
Cytochrome P450, family 39, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
      
 0.775
rsf1b.1-2
Remodeling and spacing factor 1b, tandem duplicate 1.
      
 0.736
tdrd6
Tudor domain-containing 6; Tudor domain-containing protein involved in germ cell development, more specifically the formation of chromatoid body (during spermiogenesis), Balbiani body (during oogenesis), germ plasm (upon fertilization), and for proper miRNA expression and spliceosome maturation (By similarity). Required for Balbiani body and germ plasm formation and mobility through interaction with dimethylated arginines in the prion-like protein Bucky ball (buc). Coordinates transcript deposition into future primordial germ cells. Interacts with known germ plasm mRNAs such as vasa, d [...]
      
 0.717
rsf1b.1
Remodeling and spacing factor 1b, tandem duplicate 1.
      
 0.662
elmod2
ELMO/CED-12 domain-containing 2.
      
 0.559
slc25a27
Solute carrier family 25 member 27; Belongs to the mitochondrial carrier (TC 2.A.29) family.
 
    
 0.486
rab33a
RAB33A, member RAS oncogene family.
      
 0.449
ppme1
Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.
      
 0.412
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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