STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slc2a1aFacilitated glucose transporter 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (488 aa)    
Predicted Functional Partners:
LOC100334818
MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
 
 
0.904
slc2a1b
Solute carrier family 2 member 1b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
 
0.903
slc7a1a
Solute carrier family 7 member 1a.
   
 
 0.687
SLC7A1
Solute carrier family 7 member 1.
   
 
 0.687
slc7a5
Solute carrier family 7 member 5.
   
 
 0.663
mfsd2aa
Sodium-dependent lysophosphatidylcholine symporter 1-A; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and [...]
     
 0.662
gapdh
Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...]
    
 0.662
eno1a
Enolase 1a, (alpha).
   
  
 0.626
eno3
Enolase 3, (beta, muscle).
   
  
 0.625
ldha
L-lactate dehydrogenase A chain; Belongs to the LDH/MDH superfamily. LDH family.
     
 0.607
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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