Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cahzCarbonic anhydrase; Reversible hydration of carbon dioxide. (260 aa)    
Predicted Functional Partners:
slc4a1a
Anion exchange protein.
   
 
 0.793
ca7
Carbonic anhydrase VII; Belongs to the alpha-carbonic anhydrase family.
  
  
0.711
rhcgb
Ammonium transporter Rh type C-like 2; Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill (By similarity); Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
   
  
 0.692
hbae1.1
Hemoglobin, alpha embryonic 1.1.
   
  
 0.680
slc9a3.2
Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
    
 
 0.669
cabin1
Calcineurin-binding protein 1.
   
  
 0.667
uqcrc2a
Ubiquinol-cytochrome c reductase core protein 2a.
      
 0.666
stk40
Serine/threonine kinase 40.
      
 0.617
hbbe2
Hemoglobin beta embryonic-2; Belongs to the globin family.
   
  
 0.593
slc4a4a
Anion exchange protein.
    
 
 0.591
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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