Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
f9aCoagulation factor IXa. (503 aa)    
Predicted Functional Partners:
f3b
Coagulation factor IIIb.
    
 
 0.680
cyp2x7
Cytochrome P450, family 2, subfamily X, polypeptide 7; Belongs to the cytochrome P450 family.
    
 0.671
f3a
Coagulation factor IIIa.
    
 
 0.645
serpinc1
Serine (Or cysteine) proteinase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family.
   
 0.631
c3b.1
Complement component c3b, tandem duplicate 1.
    
 0.620
serpind1
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.
   
 0.601
lipca
Lipase, hepatic a.
   
 
 0.560
cpt1ab
Carnitine palmitoyltransferase 1Ab (liver); Belongs to the carnitine/choline acetyltransferase family.
   
  
 0.560
ENSDARP00000141525
Si:ch1073-416d2.3; Belongs to the serpin family.
   
 0.537
f2
Coagulation factor II (thrombin); Belongs to the peptidase S1 family.
  
 
0.532
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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