Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
icmtProtein-S-isoprenylcysteine O-methyltransferase. (292 aa)    
Predicted Functional Partners:
rce1b
Ras-converting CAAX endopeptidase 1b.
   
 0.989
rce1a
Ras-converting CAAX endopeptidase 1a.
   
 0.984
zmpste24
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
    
 0.981
ENSDARP00000151202
Peptidase_M48_N domain-containing protein.
    
 0.938
rfk
Riboflavin kinase.
     
 0.821
fnta
Farnesyltransferase, CAAX box, alpha.
      
 0.815
flad1
Molybdenum cofactor biosynthesis protein-like region; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme; In the N-terminal section; belongs to the MoaB/Mog family.
     
 0.797
gpr153
G protein-coupled receptor 153.
 
    
 0.787
pudp
Pseudouridine 5'-phosphatase.
     
 0.754
tbccd1
TBCC domain-containing protein 1; May play a role in the regulation of centrosome and Golgi apparatus positioning; Belongs to the TBCC family.
      
 0.745
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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