Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tmem179aaTransmembrane protein 179. (232 aa)    
Predicted Functional Partners:
tbc1d8
Uncharacterized protein.
      
 0.878
MZT1
Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome.
      
 0.872
exd2
Exonuclease 3'-5' domain-containing 2.
      
 0.837
bccip
Protein BCCIP homolog; During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spindle pole. May promote cell cycle arrest and DNA repair; Belongs to the BCP1 family.
      
 0.803
zbtb34
Zinc finger and BTB domain-containing 34.
      
 0.752
ubr1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
      
 0.693
fam204a
Family with sequence similarity 204 member A.
      
 0.687
thsd7aa
Thrombospondin type-1 domain-containing protein 7A; Required for normal sprouting angiogenesis and normal embryonic development of intersegmental vessels (ISV). Required for normal function of the glomerular filtration barrier. Required for normal axon outgrowth on embryonic motor neurons at the level of the horizontal myoseptum. Required for normal expression of notch1b, suggesting that its functions in angiogenesis and neuron outgrowth are due to decreased expression of notch1b. Plays a role in actin cytoskeleton rearrangement (By similarity).
      
 0.684
srp14
Signal recognition particle 14.
      
 0.683
NPAS3
Neuronal PAS domain protein 3.
      
 0.662
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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