Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
eif4e1bEukaryotic translation initiation factor 4E-1B; Does not appear to be a mRNA-cap-binding protein. (214 aa)    
Predicted Functional Partners:
eif4ebp1
Eukaryotic translation initiation factor 4E-binding protein 1.
    
 0.988
eif4ebp3l
Eukaryotic translation initiation factor 4E-binding protein 3-like; Regulates eif4e1a activity by preventing its assembly into the eIF4F complex; Belongs to the eIF4E-binding protein family.
    
 0.983
eif4g2b
Eukaryotic translation initiation factor 4, gamma 2b.
   
 0.980
mknk1
MAPK-interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily.
    
 0.978
eif4e2
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
   
0.969
eif4e2rs1
Eukaryotic translation initiation factor 4E family member 2-related sequence 1; Belongs to the eukaryotic initiation factor 4E family.
   
0.968
eif4g2a
Eukaryotic translation initiation factor 4, gamma 2a.
   
 0.954
mknk2b
MAPK-interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily.
    
 0.948
rps6
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 
 0.946
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
   
 0.942
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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