STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif4e1bEukaryotic translation initiation factor 4E-1B; Does not appear to be a mRNA-cap-binding protein. (214 aa)    
Predicted Functional Partners:
eif4ebp3l
Eukaryotic translation initiation factor 4E-binding protein 3-like; Regulates eif4e1a activity by preventing its assembly into the eIF4F complex; Belongs to the eIF4E-binding protein family.
    
 
 0.995
cyfip1
Cytoplasmic FMR1-interacting protein 1 homolog; Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA (By similarity); Belongs to the CYFIP family.
    
 0.989
eif4ebp1
Eukaryotic translation initiation factor 4E-binding protein 1.
    
 0.984
eif4ba
Eukaryotic translation initiation factor 4Ba.
   
 
 0.966
cyfip2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.963
eif4g2b
Eukaryotic translation initiation factor 4, gamma 2b.
   
 0.957
mknk1
MAPK-interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily.
    
 0.945
mknk2a
MAPK-interacting serine/threonine kinase 2a; Belongs to the protein kinase superfamily.
    
 0.926
mknk2b
MAPK-interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily.
    
 0.926
eif4g3b
Eukaryotic translation initiation factor 4 gamma, 3b.
   
 0.915
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.