STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xpnpep1X-prolyl aminopeptidase (Aminopeptidase P) 1, Soluble; Belongs to the peptidase M24B family. (620 aa)    
Predicted Functional Partners:
add3a
Adducin 3 (gamma) a.
  
  
 0.941
zmp:0000000527
Zmp:0000000527.
    
 
 0.749
unm_sa911
Un-named sa911.
    
 
 0.749
ssrp1b
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
  
 0.672
eevs
2-epi-5-epi-valiolone synthase.
    
  0.663
kcnh1a
Potassium voltage-gated channel, subfamily H (eag-related), member 1a.
      
 0.660
gpc1a
Secreted glypican-1; Cell surface proteoglycan that bears heparan sulfate; Belongs to the glypican family.
      
 0.619
gpc1b
Glypican 1b; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
      
 0.610
BOLA2
Zgc:112271 protein; Belongs to the BolA/IbaG family.
   
 
 0.570
dnpep
Aspartyl aminopeptidase; Belongs to the peptidase M18 family.
  
 
 0.548
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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