Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
xpnpep1X-prolyl aminopeptidase (Aminopeptidase P) 1, Soluble; Belongs to the peptidase M24B family. (620 aa)    
Predicted Functional Partners:
add3a
Adducin 3 (gamma) a.
  
  
 0.929
mmel1
Membrane metallo-endopeptidase-like 1.
   
 
 0.883
mep1a.2
Meprin A subunit.
   
 
 0.776
mep1a.1
Metalloendopeptidase.
   
 
 0.776
MEP1B
Meprin A subunit.
   
 
 0.772
mep1b
Meprin A subunit.
   
 
 0.772
dpp7
Dipeptidyl-peptidase 7.
   
 
 0.757
prcp
Prolylcarboxypeptidase (Angiotensinase c).
   
 
 0.757
ece1
Endothelin-converting enzyme 1.
   
 
 0.754
pitrm1
Presequence protease, mitochondrial; Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing. Has an ATP-independent activity. Specifically cleaves peptides in the range of 5 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. Degrades the transit peptides of mitochondrial proteins after their cleavage. Also degrades other unstructured peptides; Belongs to the peptidase M16 family. PreP subfamily.
   
 
 0.748
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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