Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
spon2bSpondin 2b, extracellular matrix protein. (331 aa)    
Predicted Functional Partners:
gnl2
Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
      
 0.750
slc38a10
Solute carrier family 38 member 10.
      
 0.745
fam163ba
Family with sequence similarity 163 member B, genome duplicate a.
      
 0.742
lmf1
Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.
   
  
 0.728
nrde2
NRDE-2, necessary for RNA interference, domain-containing.
      
 0.711
LOC110437736
Neuropilin (NRP) and tolloid (TLL)-like 1.
      
 0.697
neto1l
Neuropilin (NRP) and tolloid (TLL)-like 1, like.
      
 0.697
chchd7
Coiled-coil-helix-coiled-coil-helix domain-containing 7.
      
 0.697
lgals3bpb
Galectin-3-binding protein B; Promotes integrin-mediated cell adhesion.
      
 0.690
cebpg
CCAAT/enhancer binding protein (C/EBP), gamma.
      
 0.670
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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