STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hoxa2bHomeobox protein Hox-A2b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (363 aa)    
Predicted Functional Partners:
pknox1.1
Homeodomain transcription factor Prep1.
   
 
 0.768
pbx4
Pre-B-cell leukemia transcription factor 4.
   
 
 0.675
egr2b
Early growth response protein 2b; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4.
   
 
 0.673
meis1b
Myeloid ecotropic viral integration 1.
   
 
 0.619
rchy1
Ring finger and CHY zinc finger domain-containing 1.
    
 
 0.575
hoxb5b
Homeobox protein Hox-B5b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  
 
0.575
hoxb5a
Homeobox protein Hox-B5a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  
 
0.570
egr2a
Early growth response 2a.
    
 
 0.566
pbx2
Pre-B-cell leukemia homeobox 2.
    
 
 0.565
mafba
Transcription factor MafB; May act as a transcriptional activator or repressor. Involved in neurogenesis. Involved in the development of rhombomeres (r) 5 and 6 segments from their common precursor 'proto-segment' in the hindbrain. Belongs to the bZIP family. Maf subfamily.
   
 
 0.561
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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