tns1b protein (Danio rerio) - STRING interaction network

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Score

tns1b

Tensin 1b. (1707 aa)

Predicted Functional Partners:

pik3c3

0.901

inppl1a

0.738

inppl1b

0.738

ptk2ab

0.696

tln1

0.690

tln2b

0.678

gak

0.673

synj1

0.673

tmem169a

0.662

tln2a

0.656

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
gak	inppl1a	ENSDARP00000111020	ENSDARP00000129999	Cyclin G-associated kinase.	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	0.573
gak	inppl1b	ENSDARP00000111020	ENSDARP00000142592	Cyclin G-associated kinase.	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	0.573
gak	pik3c3	ENSDARP00000111020	ENSDARP00000092039	Cyclin G-associated kinase.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.583
gak	synj1	ENSDARP00000111020	ENSDARP00000122252	Cyclin G-associated kinase.	Synaptojanin 1.	0.794
gak	tns1b	ENSDARP00000111020	ENSDARP00000023241	Cyclin G-associated kinase.	Tensin 1b.	0.673
inppl1a	gak	ENSDARP00000129999	ENSDARP00000111020	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	Cyclin G-associated kinase.	0.573
inppl1a	inppl1b	ENSDARP00000129999	ENSDARP00000142592	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	0.945
inppl1a	synj1	ENSDARP00000129999	ENSDARP00000122252	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	Synaptojanin 1.	0.803
inppl1a	tns1b	ENSDARP00000129999	ENSDARP00000023241	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	Tensin 1b.	0.738
inppl1b	gak	ENSDARP00000142592	ENSDARP00000111020	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	Cyclin G-associated kinase.	0.573
inppl1b	inppl1a	ENSDARP00000142592	ENSDARP00000129999	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	0.945
inppl1b	synj1	ENSDARP00000142592	ENSDARP00000122252	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	Synaptojanin 1.	0.803
inppl1b	tns1b	ENSDARP00000142592	ENSDARP00000023241	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...]	Tensin 1b.	0.738
pik3c3	gak	ENSDARP00000092039	ENSDARP00000111020	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Cyclin G-associated kinase.	0.583
pik3c3	ptk2ab	ENSDARP00000092039	ENSDARP00000042715	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.636
pik3c3	tns1b	ENSDARP00000092039	ENSDARP00000023241	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Tensin 1b.	0.901
ptk2ab	pik3c3	ENSDARP00000042715	ENSDARP00000092039	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.636
ptk2ab	tln1	ENSDARP00000042715	ENSDARP00000132453	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Talin 1.	0.929
ptk2ab	tln2a	ENSDARP00000042715	ENSDARP00000133467	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Talin 2a.	0.928
ptk2ab	tln2b	ENSDARP00000042715	ENSDARP00000153115	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Talin 2b.	0.928

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