STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pin4Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4; May be involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to DNA (By similarity). (128 aa)    
Predicted Functional Partners:
ttc9b
Tetratricopeptide repeat domain 9B.
   
 
 0.846
bnip1a
BCL2-interacting protein 1a.
      
 0.836
rnf44
RING finger protein 44.
    
 
 0.788
eprs1
Glutamyl-prolyl-tRNA synthetase.
  
 
 0.759
rpf1
Ribosome production factor 1; May be required for ribosome biogenesis.
   
  
 0.742
ppil1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.706
ppp2r2ba
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 
 0.676
stk10
Serine/threonine-protein kinase 10; May act as a polo kinase kinase by mediating phosphorylation of plk1; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
      
 0.675
faf2
Fas-associated factor family member 2.
 
    
 0.658
pin1
Peptidyl-prolyl cis-trans isomerase.
  
  
0.653
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.