Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rsph14Radial spoke head 14 homolog. (340 aa)    
Predicted Functional Partners:
cfap161
Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly.
   
 
 0.966
lrrc34
Leucine-rich repeat-containing 34.
    
 
 0.962
morn3
MORN repeat-containing 3.
   
 
 0.955
iqub
IQ motif and ubiquitin domain-containing.
   
 
 0.949
cfap52
Cilia and flagella-associated protein 52.
   
 
 0.935
ccdc65
Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules; Belongs to the DRC2 family.
   
 
 0.933
cyb5d1
Cytochrome b5 domain-containing protein 1; Belongs to the cytochrome b5 family.
   
 
 0.931
dnali1
Dynein, axonemal, light intermediate chain 1.
   
 
 0.906
lrrc23
Leucine-rich repeat-containing 23.
   
 
 0.903
ccdc146
Coiled-coil domain-containing 146.
   
  
 0.899
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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