Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nxnl2Nucleoredoxin-like 2. (156 aa)    
Predicted Functional Partners:
flii
FLII actin-remodeling protein.
      
 0.686
TXN
Thioredoxin; Belongs to the thioredoxin family.
    
 
 0.628
txn
Thioredoxin; Belongs to the thioredoxin family.
    
 
 0.628
txnl4a
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
      
 0.607
ccdc15
Coiled-coil domain-containing 15.
      
 0.558
txnl4b
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
      
 0.541
txndc15
Interferon regulatory factor 1b.
      
 0.535
stum
Protein stum homolog.
      
 0.518
nptx2b
Neuronal pentraxin IIb.
      
 0.500
sec63
SEC63 homolog, protein translocation regulator.
    
 
 0.469
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]