| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSDARP00000157381 | banp | ENSDARP00000157381 | ENSDARP00000023623 | Uncharacterized protein. | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | 0.731 |
| acap2 | banp | ENSDARP00000080366 | ENSDARP00000023623 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | 0.719 |
| banp | ENSDARP00000157381 | ENSDARP00000023623 | ENSDARP00000157381 | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | Uncharacterized protein. | 0.731 |
| banp | acap2 | ENSDARP00000023623 | ENSDARP00000080366 | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | 0.719 |
| banp | bend3 | ENSDARP00000023623 | ENSDARP00000120361 | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | BEN domain-containing 3. | 0.667 |
| banp | fars2 | ENSDARP00000023623 | ENSDARP00000136280 | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | Phenylalanyl-tRNA synthetase 2, mitochondrial. | 0.728 |
| banp | mdm2 | ENSDARP00000023623 | ENSDARP00000072320 | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. | 0.810 |
| banp | mre11a | ENSDARP00000023623 | ENSDARP00000139437 | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.710 |
| banp | setmar | ENSDARP00000023623 | ENSDARP00000101881 | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | SET domain and mariner transposase fusion protein. | 0.699 |
| banp | tcf25 | ENSDARP00000023623 | ENSDARP00000059892 | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | Transcription factor 25 (basic helix-loop-helix). | 0.693 |
| banp | tp53 | ENSDARP00000023623 | ENSDARP00000116736 | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.971 |
| banp | washc3 | ENSDARP00000023623 | ENSDARP00000066998 | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | WASH complex subunit 3. | 0.731 |
| bend3 | banp | ENSDARP00000120361 | ENSDARP00000023623 | BEN domain-containing 3. | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | 0.667 |
| fars2 | banp | ENSDARP00000136280 | ENSDARP00000023623 | Phenylalanyl-tRNA synthetase 2, mitochondrial. | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | 0.728 |
| mdm2 | banp | ENSDARP00000072320 | ENSDARP00000023623 | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | 0.810 |
| mdm2 | tp53 | ENSDARP00000072320 | ENSDARP00000116736 | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.999 |
| mre11a | banp | ENSDARP00000139437 | ENSDARP00000023623 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | 0.710 |
| mre11a | tp53 | ENSDARP00000139437 | ENSDARP00000116736 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.985 |
| setmar | banp | ENSDARP00000101881 | ENSDARP00000023623 | SET domain and mariner transposase fusion protein. | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | 0.699 |
| tcf25 | banp | ENSDARP00000059892 | ENSDARP00000023623 | Transcription factor 25 (basic helix-loop-helix). | Protein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. | 0.693 |