Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
neurod2Neurogenic differentiation factor 2; Transcriptional regulator. Appears to mediate neuronal differentiation (By similarity). (363 aa)    
Predicted Functional Partners:
eomesa
T-box transcription factor eomesodermin.
   
 
 0.518
fezf2
Fez family zinc finger protein 2; Transcription repressor. Component of the regulatory cascade that controls the development of dopaminergic (DA) and serotonergic (5HT) neurons.
   
 
 0.509
tbr1b
T-box brain transcription factor 1b.
   
 
 0.504
tcf3a
Transcription factor 3a.
    
 
 0.473
tcf3b
Transcription factor 3b.
    
 
 0.473
tcf12
Transcription factor 12.
    
 
 0.473
ENSDARP00000150042
Uncharacterized protein.
    
 
 0.473
TCF4
Transcription factor 4.
    
 
 0.473
pax6a
Paired box protein Pax-6; Transcription factor expressed in spatially restricted regions of the neural tube during embryonic development; Belongs to the paired homeobox family.
   
 
 0.465
vsx1
Visual system homeobox 1; May be involved in maintenance as well as cellular differentiation of retinal interneurons, such as bipolar cells. May play a role in establishing interneuronal cell classes in nonsensory as well as sensory systems; Belongs to the paired homeobox family.
   
 
 0.458
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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