Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
dbx1aHomeobox protein DBX1-A; Belongs to the H2.0 homeobox family. (314 aa)    
Predicted Functional Partners:
lhx5
LIM/homeobox protein Lhx5; Probably involved in the patterning of the nervous system, in particular in the early specification of the diencephalon.
   
 
 0.631
irx3a
Iroquois 3 homeobox protein.
   
 
 0.570
prdm12b
PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily.
   
  
 0.565
lrp4
Low density lipoprotein receptor-related protein 4.
      
 0.551
htatip2
HIV-1 Tat interactive protein 2.
   
  
 0.534
olig2
Oligodendrocyte lineage transcription factor 2.
   
  
 0.526
prmt3
Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
      
 0.505
kidins220a
Kinase D-interacting substrate 220a.
      
 0.488
olig4
Oligodendrocyte transcription factor 4.
   
  
 0.473
elavl3
ELAV-like protein; Belongs to the RRM elav family.
   
  
 0.469
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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