STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ism1Isthmin-1; May specifically influence certain angiogenesis process. (461 aa)    
Predicted Functional Partners:
sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
 
 
 0.923
SUSD2
Sushi domain containing 2.
      
 0.859
kif16bb
Kinesin family member 16Bb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.839
kdsr
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.740
sord
Sorbitol dehydrogenase.
  
 
 0.740
btbd3a
BTB (POZ) domain-containing 3a.
      
 0.720
tasp1
Taspase, threonine aspartase, 1.
      
 0.678
fkbpl
FKBP prolyl isomerase-like.
   
  
 0.671
ndr1
Nodal-related 1.
      
 0.648
ormdl1
ORM1-like protein 1; Negative regulator of sphingolipid synthesis; Belongs to the ORM family.
    
 
 0.588
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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