Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (429 aa)    
Predicted Functional Partners:
idh3a
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.998
aco2
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.996
idh3b
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.994
idh3g
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.993
aco1
Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family.
  
 0.990
ogdhl
Oxoglutarate dehydrogenase-like.
   
 0.985
ogdha
Oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide).
   
 0.983
cs
Citrate synthase, mitochondrial.
  
 0.980
ireb2
Iron-responsive element-binding protein 2; Belongs to the aconitase/IPM isomerase family.
  
 0.976
idh2
Isocitrate dehydrogenase (NADP(+)) 2.
   
 0.972
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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