node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bckdha | bckdhb | ENSDARP00000059346 | ENSDARP00000157432 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.999 |
bckdha | h6pd | ENSDARP00000059346 | ENSDARP00000124115 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). | 0.701 |
bckdha | pdhb | ENSDARP00000059346 | ENSDARP00000002122 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.999 |
bckdha | rpe | ENSDARP00000059346 | ENSDARP00000023863 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.942 |
bckdha | rpia | ENSDARP00000059346 | ENSDARP00000073610 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase). | 0.934 |
bckdha | taldo1 | ENSDARP00000059346 | ENSDARP00000143071 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.941 |
bckdha | tkta | ENSDARP00000059346 | ENSDARP00000045887 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Transketolase a. | 0.886 |
bckdha | tktb | ENSDARP00000059346 | ENSDARP00000017569 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Transketolase b. | 0.885 |
bckdhb | bckdha | ENSDARP00000157432 | ENSDARP00000059346 | Branched chain keto acid dehydrogenase E1 subunit beta. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |
bckdhb | h6pd | ENSDARP00000157432 | ENSDARP00000124115 | Branched chain keto acid dehydrogenase E1 subunit beta. | Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). | 0.714 |
bckdhb | pdhb | ENSDARP00000157432 | ENSDARP00000002122 | Branched chain keto acid dehydrogenase E1 subunit beta. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.568 |
bckdhb | rpe | ENSDARP00000157432 | ENSDARP00000023863 | Branched chain keto acid dehydrogenase E1 subunit beta. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.922 |
bckdhb | rpia | ENSDARP00000157432 | ENSDARP00000073610 | Branched chain keto acid dehydrogenase E1 subunit beta. | Ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase). | 0.903 |
bckdhb | taldo1 | ENSDARP00000157432 | ENSDARP00000143071 | Branched chain keto acid dehydrogenase E1 subunit beta. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.920 |
bckdhb | tkta | ENSDARP00000157432 | ENSDARP00000045887 | Branched chain keto acid dehydrogenase E1 subunit beta. | Transketolase a. | 0.545 |
bckdhb | tktb | ENSDARP00000157432 | ENSDARP00000017569 | Branched chain keto acid dehydrogenase E1 subunit beta. | Transketolase b. | 0.559 |
h6pd | bckdha | ENSDARP00000124115 | ENSDARP00000059346 | Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.701 |
h6pd | bckdhb | ENSDARP00000124115 | ENSDARP00000157432 | Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.714 |
h6pd | pdhb | ENSDARP00000124115 | ENSDARP00000002122 | Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.938 |
h6pd | pgd | ENSDARP00000124115 | ENSDARP00000007588 | Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.999 |